Telbivudine treatment started in early and middle pregnancy completely blocks HBV vertical transmission
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منابع مشابه
Telbivudine treatment started in early and middle pregnancy completely blocks HBV vertical transmission
BACKGROUND To evaluate the efficacy and safety of treating HBV-positive mothers with telbivudine in early and middle pregnancy to prevent mother-to-infant HBV transmission. METHODS The subject population comprised pregnant women with chronic hepatitis B (CHB; n = 188) from January 2013 to June 2015, with HBV DNA ≥1.0 × 107copies/mL and increased alanine aminotransferase levels. Groups A (n = ...
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Title: Telbivudine treatment started in early and middle pregnancy completely blocks HBV vertical transmission Authors: Weihui Sun ([email protected]) Zhao Shangfei ([email protected]) Ma Lei ([email protected]) Hao Anhua ([email protected]) Zhao Bo ([email protected]) Zhou Lin ([email protected]) Qu Qiaoyan ([email protected]) Song Mingquan ([email protected]) Xin Yongning (xinyongni...
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Background: Primary infection with the BK virus occurs in the tonsils and is transmitted to other tissues and organs, especially the kidneys, by infecting monocytes. Infection with this virus is rarely associated with clinical disease but reactivating the virus in people who have a suppressed immune system can cause kidney or bladder damage. Due to the importance of activating the BK virus in s...
متن کاملHBV treatment and pregnancy.
The management of hepatitis B virus (HBV) infection in pregnancy is complex. Because infection with HBV in infancy often leads to chronic disease, prevention of perinatal or vertical transmission is a major goal. Worldwide, vertical transmission remains the most frequent route of infection, particularly in endemic areas where up to 20% of women of childbearing age may have HBV. These women cons...
متن کاملTelbivudine during the second and third trimester of pregnancy interrupts HBV intrauterine transmission: a systematic review and meta-analysis.
UNLABELLED BECKGROUND: Evaluate the efficacy and safety of telbivudine during the 2nd and 3rd trimester of pregnancy in intrauterine transmission of hepatitis B virus (HBV). Based on the principle of Cochrane systematic reviews, a database was constructed from Medline, EMBASE, Cochrane Library, the US National Science Digital Library (NSDL), the China Biological Medicine Database (CBM-disc), an...
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ژورنال
عنوان ژورنال: BMC Gastroenterology
سال: 2017
ISSN: 1471-230X
DOI: 10.1186/s12876-017-0608-7